Caseous lymphadenitis

 

Caseous lymphadenitis

Etiology:-

Corynebacterium pseudotuberculosis

·         Common in sheep and goat

·         Also exist in a horse called ulcerative lymphadenitis

·         It also causes contagious acne in horse

·         ulcerative lymphadenitis clinically similar to Glander in horse

Bacterial characteristics:-

Highly resistance bacteria

It produces the toxin phospholipase, which hydrolyzes the sphingomyelin sheath of macrophages due to which survive the phagocytosis that’s why resistance to immune and environment

Pathogenesis:-

Those animals which are grazing

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Get the injury and common inhabitant (Corynebacterium) cause the infection

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Prefemoral nodules

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Pus formation

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Caseous yellowish in color

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Swell the nymph nodes of heard area.

            Mostly in cervical in goat but in sheep effect any gland (because shearing occurs, injury at any site.

Common inhabitant is skin and soil and survives for four months.

In fomites survive for two months.

 Shed in nasal and oral secretions

Discharge from the rupture lymph node.

Clinical finding:-

·         Enlargement of superficial lymph node (mainly cervical) sub-maxillary pre-scapular parotid lymph node in other animals pre-femoral and supra-mammary lymph node also enlargement.

·         Rupture of mature abscesses and discharge of various consistency on rupture, caseous pus discharge without any smell.

·         Loss of hair at that site

·         In systemic cases   when lymph node attach with organ

·         Chronic pneumonia pyelonephritis

·         Ataxia

·         Paraplegia (paralysis of single side)

·         Poor body condition (in the chronic form called the thin ewe syndrome)

·         Enlargement of supra-mammary lymph node

·         A decrease in milk production 

Treatment:-

·         Highly resistance bacteria

·         Mature abscess by iodex and hot therapy

·         Penicillin + tetracycline are used